{"product_id":"gentamicin-sulfate-antibiotic-g3632","title":"Merck Millipore Gentamicin Sulfate","description":"\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cspan\u003eGentamicin sulfate is a broad-spectrum aminoglycoside antibiotic derived from \u003c\/span\u003e\u003cem\u003e\u003cspan\u003eMicromonospora purpurea\u003c\/span\u003e\u003c\/em\u003e\u003cspan\u003e that provides effective bactericidal activity against Gram-negative bacteria, Gram-positive bacteria, and mycoplasma. It serves as a versatile choice for preventing bacterial contamination and as a selective agent in cell culture, molecular biology, and advanced drug delivery applications.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cspan\u003eThis formulation (Cat. No. G3632) is supplied as a white to off-white powder with a potency of ≥590 IU (units) of gentamicin base per mg. The recommended working concentration for eukaryotic cell culture is 50 μg\/mL, prepared in water. Gentamicin is freely soluble in water and practically insoluble in ethanol.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cspan\u003eThe antibiotic exerts its bactericidal effect by binding to the 30S ribosomal subunit, causing codon misreading and inhibiting peptidyl-tRNA translocation from the acceptor site to the donor site. It also disrupts the outer membrane of \u003c\/span\u003e\u003cem\u003e\u003cspan\u003ePseudomonas aeruginosa\u003c\/span\u003e\u003c\/em\u003e\u003cspan\u003e by displacing natural cations, leading to membrane destabilization and pore formation. Gentamicin is active against a broad spectrum of bacteria, including strains resistant to tetracycline, chloramphenicol, kanamycin, and colistin.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cspan\u003eGentamicin sulfate is suitable for use in cell culture media, bacterial selection systems (gentamicin resistance genes), and advanced drug delivery research. Store at 2–8°C in a tightly closed, dry container; solutions are stable under these conditions for extended periods. This product is intended for research use only and is not for diagnostic or therapeutic use in humans or animals.\u003c\/span\u003e\u003c\/p\u003e","brand":"Merck Millipore","offers":[{"title":"250 mg","offer_id":52815664480584,"sku":"G3632-250MG","price":56.0,"currency_code":"GBP","in_stock":true},{"title":"1 g","offer_id":52815664513352,"sku":"G3632-1G","price":90.0,"currency_code":"GBP","in_stock":true},{"title":"5 g","offer_id":52815664546120,"sku":"G3632-5G","price":443.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0906\/7570\/8232\/files\/unnamed_1_3d9cafb1-fb38-4936-83bf-9beb823fc1ba.jpg?v=1774461616","url":"https:\/\/cellbase.com\/products\/gentamicin-sulfate-antibiotic-g3632","provider":"Cellbase","version":"1.0","type":"link"}