Optimising Cell Lines for Serum-Free Media with Gene Editing
If I remove serum but keep the same wild-type cell line, I should not expect media tuning alone to stop senescence, drift, or attachment loss. In this article, I show...
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Alicat Scientific | SKU:
Alicat Bio-Series Mass Flow Controller
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£2,643.00
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Availability
In stock. Ships globally direct from Alicat Scientific to research and production facilities.
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Purchase includes full technical documentation (CoAs, Manuals, or Protocols) provided automatically. Direct application support included from Alicat Scientific to ensure successful implementation.
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Purchase orders also accepted. Select bank transfer at checkout and provide your PO number in order notes or email to sales@cellbase.com
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Most products require no additional agreements. Cell lines and certain biological materials require a Material Transfer Agreement (MTA) on first purchase from each supplier. We handle this digitally - both parties sign online before shipment. Subsequent orders from the same supplier proceed immediately.
The Alicat Bio-Series Mass Flow Controller is a specialized gas management solution engineered specifically for the rigorous demands of bioprocessing and fermentation. Building on Alicat’s proven laminar differential pressure technology, the Bio-Series delivers an exceptional 10,000:1 turndown ratio (operating range), allowing a single device to manage both fine sparging and high-volume headspace aeration. This versatility eliminates the need for multiple gas lines, simplifying bioreactor setups from lab-scale to production.
Safety and sterility are paramount in biopharmaceutical environments. The Bio-Series features USP Class VI FDA-certified Viton elastomers and a robust 316L stainless steel flow path to ensure process purity and compatibility with stringent cleaning protocols. With a control response time of just 10ms, these controllers provide near-instantaneous stabilization of dissolved oxygen (DO) and pH levels, protecting sensitive cell cultures from gas spikes or instabilities.
Designed for modern smart-factories, the Bio-Series comes standard with integrated industrial protocols including EtherNet/IP and Modbus-TCP, facilitating seamless integration with PLC systems and bioprocess software. The on-board display provides real-time visibility of mass flow, volumetric flow, pressure, and temperature. Whether you are scaling up a mammalian cell line or optimizing microbial fermentation, the Alicat Bio-Series provides the precision, speed, and regulatory compliance required for successful bioprocessing.
For biopharmaceutical research and production. NIST-traceable calibration and USP Class VI compliance documentation included.
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Regulatory complianceUSP Class VI FDA-certified elastomers, NIST-traceable, CE, RoHS
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Scale compatibilityLab scale, Pilot scale, Production scale
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Storage temperature
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Validation status
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Application specific
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Dimensions (H×W×D cm)
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Mixing system typeIntegrated Proportional Control Valve
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Power requirements
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Production capacity unit
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Technology typeLaminar Differential Pressure
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Temperature Max (°C)
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Temperature Min (°C)
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Turndown ratio
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Use restriction
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Max Volume (L)
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Min Volume (L)
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Weight (kg)
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Controller Type
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Display Type
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Recipe-Based ControlYes
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Remote MonitoringYes
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Interface ConnectivityRS-232, RS-485, Modbus RTU, EtherNet/IP, Modbus TCP
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Material type
Cellag Bio is the structured intelligence layer for cultivated meat R&D — scattered published research distilled into decision-ready records: what worked, what failed, the likely cause, and what to do instead. Before committing budget to a medium, reagent, or cell line, check the evidence behind it: real experimental outcomes and failure modes, not marketing claims.
Search by media, reagent, cell line or species (e.g. "Beefy-9" or "B8") to find the records that use it.
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