Energy Efficiency in Bioreactor Scale-Up Processes
Scaling up bioreactors for cultivated meat production - from small (1–5 L) to large (1,000+ L) systems - brings energy challenges. Larger volumes require more power for mixing, oxygen transfer,...
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Defined Bioscience
Defined Bioscience HiDef® PBS/EDTA Cell Dissociation Reagent
Specialised equipment for efficiently separating and collecting cultured cells from bioreactor systems. These systems maintain cell viability whilst achieving high recovery rates essential for commercial production economics.
Gentle harvesting technologies preserve cell integrity and functionality through the collection process. Automated systems reduce labour requirements and improve consistency in commercial operations.
Scalable from laboratory to production volumes with appropriate throughput and capacity for different production scales. All systems designed for food-grade applications with appropriate cleaning and sterilisation capabilities.
Scaling up bioreactors for cultivated meat production - from small (1–5 L) to large (1,000+ L) systems - brings energy challenges. Larger volumes require more power for mixing, oxygen transfer,...
Maintaining precise pH and temperature is critical for growing mammalian cells, especially in cultivated meat production. Cells need a controlled environment to multiply (proliferation) and develop into muscle fibres (differentiation)....
Monitoring live cells in bioreactors is critical for cultivated meat production. Scaling requires precise tools to track cell health and growth in real time. This article reviews key methods, including...
Process Analytical Technology (PAT) integrates real-time quality monitoring into manufacturing processes, improving consistency and reducing waste. It’s especially useful in cultivated meat production, where precise control of factors like pH,...
Maintaining precise temperature and humidity during transport is critical for cultivated meat. Small fluctuations can spoil shipments and lead to waste. Advanced IoT sensors now provide real-time monitoring, ensuring product...
Automated sampling systems are transforming how bioprocesses are monitored, especially in cultivated meat production. These systems offer frequent, precise, and real-time data on critical factors like nutrient levels, metabolites, and...
Scaling bioreactors for cultivated meat production is complex, especially when managing shear stress, a mechanical force that can damage mammalian cells during scale-up. Unlike microbial cells, mammalian cells are fragile...
Contamination is a major hurdle in cultivated meat production, with batch failure rates hitting 11.2% and climbing to 19.5% in larger-scale operations. This not only wastes resources like growth media...