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CultureGro™ Human PDGF-BB Animal Free Recombinant Protein

£3,133.00

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What published studies used with PDGF-BB

Components that studies in Cellag Bio used alongside PDGF-BB, and where to find them on Cellbase. Limited evidence

Bovine · Muscle cells (2)
DMEM/F12Used in 2 of 2 Cellag Bio studies
Product Image Gibco™ DMEM/F-12 Gibco · £35.00
Other options (2) Defined Bioscience DMEM/F12 Basal Medium Defined Bioscience DMEM/F12 Basal Medium Defined Bioscience · From £31.00 KCell DMEM/F12 KCell DMEM/F12 KCell · From £7.00

Also used in these studies, not currently on Cellbase: HGF, IL-6, Albumin, Alpha-linolenic acid, Ascorbic acid 2-phosphate. Ask us to source these →

How we choose these

These come from published studies in Cellag Bio. They show which components those studies used, not these exact products, and results can differ in your system. Components not yet on Cellbase are listed at the end of each section. Check specifications and compatibility with each supplier.

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PDGFs are dimers linked by disulfide bonds, composed of two 12.0-13.5 kDa polypeptide chains known as PDGF-A and PDGF-B. Among the three naturally occurring PDGFs (PDGF-AA, PDGF-BB, and PDGF-AB), they act as potent mitogens for various cell types such as smooth muscle cells, connective tissue cells, bone and cartilage cells, and certain blood cells. These growth factors are stored in platelet α-granules and are released during platelet activation, contributing to processes like hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development.

PDGFs interact with two distinct signaling receptors: PDGFR-α, a high-affinity receptor for all three PDGF forms, and PDGFR-β, which specifically interacts with PDGF-BB and PDGF-AB. Recombinant Human PDGF-BB is a 24.3 kDa disulfide-linked homodimer consisting of two β chains, totaling 218 amino acids.

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