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Defined Bioscience

Defined Bioscience Ready-CEPT® Cell Viability Enhancer

Regular price £115.00
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In stock. Ships globally direct from Defined Bioscience to research and production facilities.

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Add to cart & view shipping options / prices in checkout for your region. Orders fulfilled directly by Defined Bioscience with temperature-controlled shipping where required.

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Purchase orders also accepted. Select bank transfer at checkout and provide your PO number in order notes or email to sales@cellbase.com

Payment methods supported

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Legal

Most products require no additional agreements. Cell lines and certain biological materials require a Material Transfer Agreement (MTA) on first purchase from each supplier. We handle this digitally - both parties sign online before shipment. Subsequent orders from the same supplier proceed immediately.

Support

Defined Bioscience provides direct post-sales support including troubleshooting, process optimisation, and protocol guidance. Batch-specific documents available on request.

Defined Bioscience’s Ready-CEPT® Cell Viability Enhancer is a defined 1000× supplement formulated to improve stem-cell survival, recovery, and stability during stress events such as passaging, thawing, cryopreservation, and gene editing. The cocktail combines four protective small molecules — chroman-1 (ROCK inhibitor), emricasan (pan-caspase inhibitor), polyamines (putrescine, spermine, spermidine), and trans-ISRIB (integrated stress-response inhibitor) — to reduce apoptosis and enhance post-manipulation recovery.

Developed from CEPT technology first characterised at the U.S. National Institutes of Health, Ready-CEPT has been shown to support genetically stable stem-cell culture, single-cell cloning, and organoid formation with improved viability compared with traditional ROCK-inhibitor-only systems. It functions as a universal cytoprotective additive across mammalian and pluripotent cell lines, reducing cell death and promoting consistent colony formation.

The supplement is supplied as a sterile 1000× liquid in DMSO/water, using animal-origin-free components, and is compatible with chemically defined and serum-free media such as HiDef® B8. Each 10 µL or 200 µL vial prepares 10 mL or 200 mL of CEPT-supplemented medium respectively. Stored at –20 °C and protected from light, Ready-CEPT remains stable for up to 12 months.

For research and development use only. Not for human or diagnostic applications.

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Bank Transfer or Purchase Order

Select bank transfer at checkout to receive a proforma invoice. Purchase orders accepted. Your order processes upon payment receipt.