Immobazyme Recombinant Human Fibroblast Growth Factor Basic (FGF-2)

Immobazyme FGF-2 (Human) is a recombinant basic fibroblast growth factor designed to regulate essential cellular processes including proliferation, differentiation, and migration. Produced via precision fermentation in an E. coli expression system, this protein serves as a critical mitogen for mesenchymal, epithelial, and neuroectodermal cells, making it a vital component for serum-free media formulations in cultivated meat and tissue engineering. The protein is engineered as a monomeric fusion peptide, a design choice that enhances solubility and stability in culture environments compared to native forms.

A defining feature of this product is its verified food-grade and allergen-free status. It is manufactured without preservatives and has been rigorously tested to confirm the absence of common allergens such as soy, dairy, gluten, and shellfish, aligning with food safety standards for downstream applications. Quality control measures ensure a purity of greater than 90% via SDS-PAGE, alongside confirmed sterility and absence of mycoplasma contamination.

Functional validation using NIH-3T3 fibroblast assays demonstrates a potent, dose-dependent proliferative response, with an EC₅₀ of approximately 90 ng/mL. Comparative studies indicate that this recombinant variant achieves higher absorbance values in metabolic activity assays than standard competitor benchmarks, confirming its efficacy in driving cell expansion.

The product is supplied as a sterile lyophilised powder requiring reconstitution in sterile water. It is stable at ambient temperature for transport but should be stored at -20°C for long-term preservation. While compliant with food safety manufacturing standards, it is currently designated for research and development use.