XCeLL Factor™ TGF-β3

XCeLL Factor™ TGF-β3 is a recombinant human transforming growth factor beta-3 supplied in liquid form to support cellular differentiation, extracellular matrix deposition, and tissue organisation in defined culture systems. It plays a key role in myogenesis and fibroblast regulation, making it relevant for cultivated meat research where controlled differentiation is required for muscle development and structured tissue formation. Its activity helps guide cell fate in processes where serum components must be removed to achieve reproducible and chemically defined conditions.

The protein is produced using a human expression system and purified to high homogeneity with low endotoxin levels. This approach preserves the structural conformation and signalling activity required for consistent performance across common mammalian cell types, including fibroblasts and myocytes. The defined, animal-origin-free composition reduces variability between batches and aligns with media development strategies intended for future regulatory assessment or scale-up.

XCeLL Factor™ TGF-β3 is supplied as a ready-to-use liquid solution with confirmed solubility in dilute acidic buffers such as 4 mM HCl or 10 mM citric acid when carrier proteins are included. The format supports stable storage at low temperature and straightforward integration into basal media, supplement blends, or differentiation protocols. Its predictable activity profile allows precise dosing in workflows where fine control over cellular behaviour is required.

This growth factor is suitable for R&D and early-stage optimisation in cultivated meat, tissue engineering, and advanced cell culture applications where defined signalling inputs are essential for reproducibility and tissue-specific outcomes.