Worlds First Cultivated Meat B2B Marketplace: Read Announcement
In stock. Ships globally direct from Defined Bioscience to research and production facilities.
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Purchase orders also accepted. Select bank transfer at checkout and provide your PO number in order notes or email to sales@cellbase.com
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Most products require no additional agreements. Cell lines and certain biological materials require a Material Transfer Agreement (MTA) on first purchase from each supplier. We handle this digitally - both parties sign online before shipment. Subsequent orders from the same supplier proceed immediately.
Defined Bioscience provides direct post-sales support including troubleshooting, process optimisation, and protocol guidance. Batch-specific documents available on request.
Defined Bioscience’s HiDef® ITS Cell Culture Supplement is a chemically defined, animal-origin-free serum replacement used to maintain and support adherent cells under reduced-serum or serum-free conditions. It combines three critical components normally supplied by serum—insulin, transferrin, and sodium selenite—each optimised to sustain cell metabolism, attachment, and viability across a wide range of primary, immortalised, and stem cell types.
Insulin stimulates the uptake of glucose, amino acids, and ions to promote cell growth and prevent apoptosis. Transferrin serves as a high-affinity iron carrier and antioxidant, reducing toxicity associated with free iron exposure. Sodium selenite contributes antioxidant protection and acts as a cofactor for essential selenoenzymes. Together, these factors maintain physiological balance in nutrient-limited conditions and allow foetal bovine serum (FBS) to be reduced to four per cent or less without compromising performance.
HiDef ITS is supplied as a 100× liquid supplement in Earle’s Balanced Salt Solution (EBSS) without phenol red and prepared using fully animal-free components. It is compatible with a wide range of basal media, including Defined Bioscience’s DMEM/F12, and is validated through fibroblast outgrowth and viability testing. Each 10 mL vial is sufficient to prepare one litre of complete medium.
For research and development use only. Not for human or diagnostic applications.
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HEPES
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Stiffness customizable
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