Energy Efficiency in Bioreactor Scale-Up Processes
Scaling up bioreactors for cultivated meat production - from small (1–5 L) to large (1,000+ L) systems - brings energy challenges. Larger volumes require more power for mixing, oxygen transfer,...
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Immobazyme EGF (Human) is a recombinant epidermal growth factor designed to stimulate proliferation, differentiation, and migration in epithelial and mesenchymal cell types. Produced in an animal-free E. coli expression system, it serves as a critical signalling molecule for serum-free media formulations in cultivated meat and cellular agriculture. This specific variant is engineered as a monomeric fusion protein to provide enhanced stability and solubility compared to native forms, ensuring consistent bioactivity during extended culture periods.
A key differentiator for this product is its verified food-grade and allergen-free status. Precision fermentation manufacturing ensures the protein is free from common allergens such as soy, dairy, egg, and fish, addressing critical regulatory requirements for future food applications. The protein undergoes rigorous quality control, achieving purity levels greater than 95% via SDS-PAGE, and is confirmed negative for mycoplasma and preservatives.
Performance validation in HaCaT keratinocyte assays demonstrates significant proliferation enhancement compared to negative controls. Functional efficacy is further evidenced by scratch assays, where EGF-treated cultures achieved near-complete wound closure within 48 hours, confirming robust activity in regulating cell migration and tissue repair pathways.
The product is supplied as a sterile lyophilised powder requiring reconstitution in sterile water. It remains stable at -20°C for up to 12 months in its lyophilised state. While manufactured in compliance with food safety standards, it is currently designated for research and development use only.
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