Qkine Recombinant Bovine/Porcine TGF-β2 Protein

Qkine's food grade bovine/porcine TGF-β2 is a member of the transforming growth factor beta superfamily that regulates cell differentiation, extracellular matrix production, and tissue remodelling through SMAD-dependent signalling pathways. TGF-β signalling is critical for directing myoblast differentiation into mature muscle fibres, promoting myotube fusion, and establishing appropriate tissue architecture in cultivated meat production, while also regulating collagen synthesis and extracellular matrix organization that contribute to texture and structural integrity.

This food-grade recombinant protein is produced in E. coli expression systems and purified to >98% purity by SDS-PAGE quantitative densitometry. Manufactured in the UK under a HACCP food manufacturing regime, the protein is animal-origin-free (AOF), carrier protein-free, and tag-free to ensure exceptional purity and lot-to-lot consistency suitable for food applications. Comprehensive quality control includes mass spectrometry confirmation of expected molecular weight, recovery testing from stock vials (>95%), endotoxin analysis (<0.05 EU/μg protein), and full traceability documentation including certificates of analysis, certificates of origin, allergen analysis, beta-lactam-free certification, and animal-origin-free verification.

This protein is supplied lyophilized and should be reconstituted in 10 mM HCl or phosphate buffer at concentrations above 50 µg/mL, with optional addition of carrier protein for enhanced stability. Single-use aliquots are recommended to maintain protein integrity, with storage at -20°C for short-term use or -80°C for long-term storage. Suitable for cultivated meat media optimization, process development, commercial-scale production, and regulatory submissions. This food-grade protein is manufactured to support novel food dossier preparation, regulatory approval processes, and commercial manufacturing under GMP-equivalent standards.