The Kbiotech BioBook Twin is a high-throughput parallel bioprocessing platform designed to accelerate the development of cultivated meat media and growth protocols. By operating two independent vessels from a single control tower, it allows for statistically robust comparative studies—such as testing two different growth factor concentrations or cell line variants—while reducing the laboratory footprint.
This dual-vessel system addresses the critical need for reproducibility and rapid screening in cellular agriculture. Each vessel, ranging from 50 mL to 20 L, maintains independent control over pH, dissolved oxygen, and temperature. This modularity enables researchers to run different vessel types simultaneously—such as a single-use vessel alongside a glass vessel—to compare performance and scalability without additional capital expenditure for standalone systems.
The BioBook Twin is powered by SmartBioFlex™ SCADA software, which is 21 CFR Part 11 compliant. This ensures that all data generated during comparative testing is secure and auditable, supporting future regulatory submissions for novel food approval. The system also features up to eight mass flow controllers per vessel for precise gas mixing strategies, essential for maintaining the oxygen and carbon dioxide levels required for high-density muscle and fat cell cultures.
The platform is compatible with advanced Process Analytical Technology (PAT), including inline Raman spectroscopy for metabolite profiling and LIVE-CELL™ capacitance sensors for real-time viability monitoring. These insights are vital for developing efficient fed-batch or continuous perfusion processes that drive down the cost of cultivated meat production.
Suitable for high-throughput screening, media optimisation, and process development. The BioBook Twin provides the comparative data necessary to refine production parameters before scaling to industrial volumes.