Energy Efficiency in Bioreactor Scale-Up Processes
Scaling up bioreactors for cultivated meat production - from small (1–5 L) to large (1,000+ L) systems - brings energy challenges. Larger volumes require more power for mixing, oxygen transfer,...
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KCell Leibovitz’s L-15 Medium is formulated for the cultivation of cells in non-CO₂ environments. It replaces sodium bicarbonate with phosphate buffering and uses free-base amino acids to maintain physiological pH, allowing cultures to thrive in sealed or open-air conditions. L-15 supports a wide range of mammalian cell types, including fibroblasts, epithelial cells, and tissue explants, and is particularly suited to field or transport applications where CO₂ control is limited.
Produced under ISO and cGMP standards, KCell Leibovitz’s L-15 offers reliable composition and batch reproducibility. It is supplied in liquid or powder form, with optional inclusion of L-glutamine, phenol red, and sodium pyruvate to accommodate different experimental setups. Each batch is validated for sterility, pH stability, and osmolarity before distribution.
The medium’s self-buffering chemistry provides stable pH and nutrient conditions across extended culture periods, making it ideal for cultivated-meat, tissue-engineering, and general mammalian cell-culture workflows performed outside conventional incubator environments.
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